Queen Isabella I

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Isabella died on November 26, 1504 in Medina del Campo.  In her will she asked that her successors protect and treat the people of the Americas the same as they would the Spanish people.  Her husband continued to rule for 12 more years until he died in Madrigalejo on January 23, 1516.  He was succeeded to the throne by his grandson, who was the son of his daughter Joan.  This person was to become Holy Roman Emperor Charles V.

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